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. 2022 Oct 25;13:982508. doi: 10.3389/fgene.2022.982508

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Copyright © 2022 Feresin, Stampalija, Cappellani, Bussani, Faletra, Murru, Ulivi, Suergiu, Savarese, Pedicini, Policicchio, Ruggiero, Bosio, Savarese and Ardisia.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cytogenetic and cytogenomic analyses on amniotic fluid of Case 2. (A) GTG banding karyotype shows a complete T21; (B) SNP-array shows a complete T21. Log ratio >0 indicates a copy number gain for chromosome 21.