Skip to main content
. 2022 Nov 4;15:3493–3507. doi: 10.2147/JPR.S378876

Table 3.

Effect of 2-PG on Capsaicin Responses

2-PG Concentration µMol 0 0.0001 0.001 0.01 0.1 1 5 10 30 60 100
Capsaicin Response Amplitude 340/380 Ratio mean ± sem 0.16 ± 0.01 0.13 ± 0.01 0.08 ± 0.02 0.12 ± 0.03 0.13 ± 0.02 0.11 ± 0.03 0.17 ± 0.01 0.16 ± 0.05 0.18 ± 0.01 0.16 ± 0.04 0.19 ± 0.03
Capsaicin Response Latency Seconds mean ± sem 1.77 ± 0.3 284.7 ± 21 331.6 ± 25 302.6 ± 27 272.5 ± 17 328.2 ± 16 299.2 ± 33 404.9 ± 57 254 ± 36 351 ± 33 347 ± 47
N Rats 16 3 3 4 5 6 7 6 6 3 6
Total no. Neurons 176 19 16 26 49 35 88 66 70 42 68

Notes: Data showing the increased capsaicin response latency in the presence of 2-PG from 0.0001 to 100 µMol. Effects on capsaicin response amplitude were similar to control values.