Table 3. Echocardiography indices in the Dnajb6+/- mice compared to WT controls at 1 year.
| WT | Dnajb6+/- | p alue | |
|---|---|---|---|
| Mice number (n) | 6 | 6 | |
| HR (bpm) | 481±16 | 447±11 | 0.0017 |
| IVSd (mm) | 0.73±0.08 | 0.80±0.06 | 0.0895 |
| LVIDd (mm) | 3.92±0.33 | 3.71±0.18 | 0.2022 |
| LVPWd (mm) | 0.80±0.05 | 0.81±0.03 | 0.5204 |
| IVSs (mm) | 1.10±0.0.07 | 1.11±0.08 | 0.7878 |
| LVIDs (mm) | 2.95±0.26 | 2.77±0.15 | 0.1821 |
| LVPWs (mm) | 1.11±0.06 | 1.21±0.12 | 0.1000 |
| LVEF (%,Cube) | 57.17±5.95 | 58.17±3.92 | 0.7380 |
| LVEF (%, Teich) | 55.50±5.82 | 56.67±4.23 | 0.6996 |
| LVFS (%) | 24.67±3.61 | 25.17±2.32 | 0.7813 |
| LVd Mass (g) | 0.69±0.01 | 0.68±0.01 | 0.7650 |
| LVs Mass (g) | 0.69±0.01 | 0.69±0.01 | 1.0000 |
HR, heart rate; bpm, beats per minute; IVSd, Interventricular septum thickness at end–diastole; LVIDd, left ventricular internal dimension at end-diastole; LVPWd, left ventricular internal dimension at end-diastole; IVSs, Interventricular septum thickness at end–systole; LVIDs, Left ventricular internal dimension at end-systole; LVPWs, Left ventricular posterior wall thickness at end–diastole; LVEF, left ventricular ejection fraction; LVFS, left ventricular fractional shortening; LVd, left ventricular at end-diastole; LVs, left ventricular at end-systole. Unpaired 2-tailed student’s t-test.