Table 2.
Nivolumab + Ipilimumab vs. Pembrolizumab + Axitinib | Pembrolizumab + Axitinib vs. Avelumab + Axitinib | Nivolumab + Ipilimumab vs. Avelumab + Axitinib | |
---|---|---|---|
Incremental cost | ($13,041.03) | ($92,285.19) | ($105,326.22) |
Incremental benefit | 0.27 | 0.82 | 1.09 |
Incremental cost-effectiveness ratio | ($47,504.73) | ($113,015.87) | ($96,533.11) |
Net monetary benefit | $54,219.14 | $214,770.44 | $268,989.58 |
Net health benefit | 0.36 | 1.43 | 1.79 |
bilistic sensitivity analysis was conducted using 10,000 Monte Carlo simulations fluctuating the model parameters over realistic probability distributions.