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. Author manuscript; available in PMC: 2023 Apr 30.
Published in final edited form as: J Mol Biol. 2022 Jan 4;434(8):167440. doi: 10.1016/j.jmb.2021.167440

Table 2.

Yield and rate constant kobs of tRNA +1 frameshifting by E. coli tRNAs

During translocation in the G37-state
Pro(UGG) (ProM) Pro(GGG) (ProL) SufB2
Yield (%) 5.9 1.2 90
kobs (s−1) 0.06 0.14 0.09
During translocation in the m1G37-state or native-state
Yield (%) 3.0 0.6 30
kobs (s−1) 0.03 0.5 Not determined
During P-site occupancy in the G37-state
Yield (%) 38 26 Not determined
kobs (s−1) 0.005 0.002 Not determined
During P-site occupancy in the m1G37-state or native-state
Yield (%) 5 8 Not determined
kobs (s−1) 0.00002 0.013 Not determined

All of the values are obtained from previous work [60, 61, 64] and are presented without the statistical error of each number. The mRNA coding sequence based on which these values were derived from was 5’-AUG-CCC-CGU-U. In cases where values of both the m1G37-state or the native-state are both available, those of the native-state are presented.