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. 2022 Oct 26;15:937350. doi: 10.3389/fnmol.2022.937350

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Copyright © 2022 Sun, Baker, Wilson, Brady, Mychasiuk, Yamakawa, Vo, Wilson, McDonald and Shultz.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Study timeline. One week after the ICV cannulation, rats were implanted with an osmotic pump and immediately received either a LI induced mTBI or sham injury. Rats received the VEGF-A or VEH treatment throughout the study. Behavioral testing was conducted over the subsequent 10 days, and post-mortem analysis was conducted at 11 days after the injuries.