Fig. 4.

Box plots of association of change in diffusion tensior imaging metrics with ischemic lesion load (ILL). Top row (from left to right): change of fractional anisotropy, axial diffusivity, mean diffusivity and radial diffusivity from baseline to 6 months in the body of corpus callosum in ILL groups I, II and III. Bottom row (from left to right): change of fractional anisotropy and mean diffusivity from baseline to 6 months in the left cingulate gyrus; change of axial diffusivity and mean diffusivity from baseline to 6 months in the splenium of the corpus callosum in ILL groups I, II and III. (Red line = median; top of box = 25th percentile; bottom of box = 75th percentile; plotted whisker = the most extreme data value that is not an outlier; red cross = outlier). ^*p-values from repeated measures analysis of variance across ILL groups. ^¥p-value from post hoc analysis indicating significant between-group difference