Table 1.

PICOS components, inclusion and exclusion criteria, and search keywords used for the study selection

Components	Inclusion criteria	Exclusion criteria
Participants	Adult patients with skeletal class III malocclusion	Patients with craniofacial anomalies and/or skeletal asymmetries
	Keyword: Skeletal class III malocclusion, skeletal class III, mandibular prognathism, mandibular protrusion, mandibular hyperplasia, maxillary retrusion, maxillary hypoplasia, maxillary retrognathism, angle class III
Intervention	Orthognathic	Orthopedic or interceptive or early treatment
	Keyword: Orthognathic surgery, orthognathic surgeries, maxillofacial orthognathic surgery, maxillofacial orthognathic surgeries, orthognathic surgical procedure, orthognathic surgical procedures, mandibular surgery, mandibular surgeries, surgical procedure, surgical procedures, jaw surgery, jaw surgeries
Comparator	Orthodontic camouflage	Studies with no control group
	Keyword: Orthodontic treatment, camouflage treatment, comprehensive treatment, adult treatment
Outcome	Primary outcome: skeletal change Secondary outcomes: dentoalveolar and soft tissue changes	Outcomes other than skeletal and dentoalveolar and soft tissue changes
Study design	Longitudinal (retrospective or prospective) studies, and controlled and non-controlled clinical trials	Case reports, case series, literature reviews, systematic review, opinion articles, book chapters