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. 2022 Oct 26;16:997360. doi: 10.3389/fncel.2022.997360

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Copyright © 2022 Ge, Cai and Pan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Persistent pain activates BLA–CeAl inputs, not PBN–CeAl inputs in dual-input CeAl cells. (A) Group data of cell percentages for dual-input cells, PBN-input-only cells, BLA-input-only cells and none-input cells in CeAl from rats injected with saline or CFA. (B,C) BLA-elicited eEPSC traces (B) and group data of the eEPSC amplitude (C) in the dual-input CeAl cells from the saline- and CFA-injected rats. (D,E) PBN-elicited lEPSC traces (D) and group data of the lEPSC amplitude (E) in the dual-input CeAl cells from the saline- and CFA-injected rats. (F–J) mEPSC traces (F) and group data of mEPSC amplitude (G,H) and mEPSC frequency (I,J) in the dual-input CeAl cells from the saline and CFA rat groups. (K,L) Representative current traces of AMPA EPSCs and NMDA EPSCs (K), and group data of AMPA/NMDA ratio (L) in the saline and CFA groups. *p < 0.05 and **p < 0.01.