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Identification of the BGC and pathway of 1 and 2. (A) The rum gene cluster in A. umbrinum. (B) LC–MS analysis of products profiles of heterologous expression of different combinations of rum genes in A. nidulans. (C) Putative biosynthetic pathway of 1 and 2. AT, acyl transferase; ACP, acyl-carrier protein; DH, dehydratase; KS, ketoacyl synthase; KR, ketoreductase; MT, methyltransferase.
