Table 1.

Effects of tacrolimus (Tacro) and vorinostat (Vorino) on basic parameters.

Groups (n = 6)	DMSO	Tacro	Vorino	TV28	TV14
ΔBW (g)	110.84 ± 3.1	45 ± 1.62∗	112.2 ± 12.4	57.5 ± 34.3	80 ± 16.1
ΔFGT (mg/dl)	9.2 ± 9.6	46.5 ± 9.6∗	27 ± 5.53	20.5 ± 3.82†	29.7 ± 6.34†
Tacro level (μg/l)	–	10.1 ± 1.48	–	11.31 ± 3	12.03 ± 1.8

Values are presented as mean ± SD. n = number of rats.

One-way ANOVA, followed by Bonferroni post hoc comparison test. P = 0.05.

DMSO, control; BW, body weight; FG, fastglucose test;Tacro, Tacrolimus; TV28, Tacrolimus with Vorinostat for 28 days; TV14, Tacrolimus for 28 days with Vorinostat for 14 days; Vorino, Vorinostat group.

^∗P = 0.05 compared with DMSO.

^†P = 0.05 compared with Tacro.