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. 2022 Oct 26;13:972012. doi: 10.3389/fimmu.2022.972012

Table 3.

Diagnostic values of criteria and non-criteria antibodies.

Sensitivity (%) Specificity (%) Accuracy (%) Youden Index PPV (%) NPV (%) OR (95%CI) PLR NLR
aCL 16.57 99.42 57.64 0.1599 96.67 53.94 33.97 (4.57, 252.40) 28.50 0.84
aβ2 GPI 34.29 98.26 65.99 0.3254 95.24 59.51 29.39 (9.00, 95.98) 19.66 0.67
LA 54.86 95.35 74.93 0.5021 92.31 67.49 24.91 (11.54, 53.78) 11.79 0.47
APhL IgG 38.86 95.35 66.86 0.3421 89.47 60.52 13.03 (6.02, 28.19) 8.35 0.64
aPS IgM 16.57 95.35 55.62 0.1192 78.38 52.90 4.07 (1.80, 9.19) 3.56 0.88
aPS/PT 45.14 94.77 69.74 0.3991 89.77 62.93 14.90 (7.15, 31.06) 8.63 0.58
APhL IgM 20.00 94.77 57.06 0.1477 79.55 53.79 4.53 (2.10, 9.75) 3.82 0.84
aPS IgG 41.04 88.95 64.93 0.2999 78.89 60.00 5.61 (3.19, 9.86) 3.72 0.66
aPE 32.57 88.37 60.23 0.2094 74.03 56.30 3.67 (2.09, 6.45) 2.80 0.76
aAnnexinV 58.86 55.81 57.35 0.1467 57.54 57.14 1.81 (1.18, 2.77) 1.33 0.74

PPV, positive predictive value; NPV, negative predictive value; OR, odds ratio; PLR, positive likelihood ratio; NLR, negative likelihood ratio; CI, confidence interval.