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. Author manuscript; available in PMC: 2023 Nov 15.
Published in final edited form as: J Immunol. 2022 Nov 15;209(10):1950–1959. doi: 10.4049/jimmunol.2200495

Figure 3: Effect of E6020 adjuvant in the antibody responses to T-dependent (NP-Ova) immunization.

Figure 3:

Age-matched C57BL/6J WT (circles), TLR4-SNP (squares), and TLR4−/− (triangles) mice were immunized using NP-Ova as a T-dependent antigen and bled as described for Figure 2. Serum IgM (top panel) and IgG (bottom panel) titers were measured by ELISA. Data were pooled from two independent experiments with 4–6 mice/treatment group/experiment. Statistical analysis (Repeated Measures 2-Way ANOVA with Sidak’s post-hoc comparison) was performed on the log transformed data.