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. Author manuscript; available in PMC: 2023 Nov 15.
Published in final edited form as: J Immunol. 2022 Nov 15;209(10):1960–1972. doi: 10.4049/jimmunol.2200543

Figure 3. Reduced NOX2 activity in neutrophils increases A. fumigatus burden following challenge with AF293.

Figure 3.

(A) Schema for AF293 challenge in indicated mice, with analysis at 72 hpi. (B) Total leukocyte and neutrophil counts from 1 ml BAL fluid. (C, D) Aspergillus CFU in 1 ml BAL fluid (C) and in homogenate of right lung (D) for the indicated mice. (E). Representative histology of lung sections for the indicated genotypes. From left to right, panels show H&E (bar 250 μm), and GMS (bar 100 μm). Arrows indicate hyphae. Data represents three independent sets of experiments with n≥5 per group. Graphical data shown as mean ± SD. Student’s ‘t’ test was performed for comparisons between 2 groups and *P<0.05, **P<0.01, ***P<0.001 ****P< 0.0001 were considered as significant.