Figure 1.

Joint effect of the Cu, Zn, Se, Co in blood on early embryonic arrest by Bayesian Kernel Machine Regression (BKMR) Model was adjusted for age, BMI, education, duration of infertility, infertility diagnosis, passive smoking and number of cycles. (A) overall effect of the Cu, Zn, Se and Co (estimates and 95% credible intervals). This plot compared the early embryonic arrest risk when Cu, Zn, Se and Co were at a particular quantile to when they were at the 50th percentile, respectively. (B) independent association of Cu, Zn, Se and Co (estimates and 95% credible intervals). This plot compared the early embryonic arrest risk when Cu, Zn, Se and Co was at the 75th of the metal concentrations with its 25th percentile, when concentrations of all the other metals were held at either the 25th (red line), 50th (green line), or 75th percentile (blue line). (C) Univariate exposure-response function and 95% confidence interval (grey part) for Cu, Zn, Se and Co when concentrations of other metals were hold at their median concentrations.