Table 1.

International Classification of Sleep Disorders, Third Edition, Diagnostic Criteria

Narcolepsy Type 1 Criteria A and B	Narcolepsy Type 2 All Criteria A-E	Central Hypersomnia due to medical disorder All Criteria A-F
A. Daily periods of irrepressible need to sleep or daytime lapses into sleep, present for at least 3 mo	A. Daily periods of irrepressible need to sleep or daytime lapses into sleep, present for at least 3 mo	A. Daily periods of irrepressible need to sleep or daytime lapses into sleep, present for at least 3 mo
B. Either 1 or 2 or both	B. Mean sleep latency ≤ 8 min and two or more SOREMPs on MSLT. REM within 15 min of sleep onset on the preceding nocturnal polysomnogram may replace one of the SOREMPs.	B. Daytime occurs as consequence of a medical condition.
1. Cataplexy and mean sleep latency ≤ 8 min and two or more SOREMPs on MSLT. REM within 15 min of sleep onset on the preceding nocturnal polysomnogram may replace one of the SOREMPs.	C. No cataplexy	C. The mean latency is ≤ 8 min), and fewer than two SOREMPs on MSLT.
2. Low CSF hypocretin-1 concentration (< 110 pg/mL or less than one-third of control values)	D. CSF hypocretin-1 concentration has not been measured or CSF hypocretin-1 concentration is ≥ 110 pg/mL or greater than one-third of control values.	D. Either 1 or 2 or both:. 1.Mean sleep latency ≤ 8 min on MSLT. 2. Total 24-h sleep time ≥ 660 min on 24-h polysomnographic monitoring or wrist actigraphy (averaged over ≥ 7 d)
	E. The hypersomnolence and/or MSLT findings are not better explained by other causes.	E. Insufficient sleep syndrome is ruled out.
		F. The hypersomnolence and/or MSLT findings are not better explained by other sleep disorder or medications.

CSF cerebral spinal fluid, MSLT multiple sleep latency test, REM rapid eye movement, SOREMP sleep-onset rapid eye movement period