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. 2022 Jul 25;45(11):zsac176. doi: 10.1093/sleep/zsac176

Table 5.

Associations between insomnia and subjective memory decline at follow-up—Analysis 2

Subjective memory
Symptom-free vs. improving symptoms Worsening symptoms vs. improving symptoms Worsening symptoms vs. symptom-free
Self-reported memory worsening
 Model 1 OR [95% CI] 0.99 [0.92–1.06] 1.27*** [1.17–1.39] 1.29*** [1.19–1.39]
 Model 2 OR [95% CI] 1.00 [0.92–1.08] 1.21*** [1.10–1.34] 1.22*** [1.12–1.33]
Self-reported diagnosed memory problem
 Model 1 OR [95% CI] 1.13 [0.74–1.74] 1.35 [0.84–2.17] 1.16 [0.78–1.72]
 Model 2 OR [95% CI] 1.09 [0.67–1.78] 0.97 [0.55–1.72] 0.85 [0.52–1.39]

OR, odds ratio; 95% CI, 95% confidence intervals.

Model 1 = adjusted for age, sex, a binary variable of total household income (>50 000 $ or ≤50 000 $), years of education, ethnicity, language, time to follow-up, and percentage loss to follow-up; Model 2 = adjusted for age, sex, a binary variable of total household income (>50 000 $ or ≤50 000 $), years of education, ethnicity, language, time to follow-up, and percentage loss to follow-up, BMI, alcohol consumption (≥4 times per week), diagnosis of cancer, anxiety disorder, clinical depression, or hypertension, current level of smoking, presence of chronic pain, activity level, a report of daytime sleepiness, a witness report of breathing interruption during sleep, a self-report of RBD, a self-report of RLS, a report of using sleep-related medications including hypnotics, antidepressants, antipsychotics, antiepileptics, antihistamines, and analgesics, as well as insufficient sleep (<6 h per night).

Bold and italicized text refers to values that pass the threshold for statistical significance.

*p < .05; **p < .01; ***p < .001.

Reference group.