Table 1:
Participant demographics by autism-behavior status
| Characteristic | Autism Unlikely (GARS AIS <70) Mean (SD) |
Autism Possible/ Very Likely (GARS AIS ≥ 70) Mean (SD) |
P value |
|---|---|---|---|
| N | 40 | 16 | |
| Sex: M/F | 19/21 | 8/8 | 0.87 |
| Age at death | 83.7 (7.9) | 79.2 (10.1) | 0.084 |
| Years of education | 17.2 (3.0) | 16.9 (3.9) | 0.76 |
| APOE4 carrier: No/Yes | 22/7 | 6/9 | 0.28 |
| GARS-2 AIS | 53.85 (9.04) | 80.50 (7.50) | N/A |
| CDR Sum of Boxes | 6.43 (4.92) | 11.53 (5.97) | 0.0017 |
| Neuropsychiatric Inventory Severity | 4.55 (4.91) | 9.63 (7.87) | 0.019 |
| Time between tests to GARS (n): | 0.3447 | ||
| 0–12 months | 22 | 11 | − |
| 13–24 months | 18 | 5 | − |
| Time between tests to autopsy (n): | 0.0538 | ||
| 0–12 months | 13 | 6 | − |
| 13–24 months | 7 | 6 | − |
| 24+ months | 20 | 4 | − |
| Clinical Diagnosis (n): | |||
| AD | 23 | 10 | − |
| VD | 2 | 1 | − |
| DLB | 2 | 2 | − |
| FTD | 2 | 2 | − |
| AD/VD | 3 | 1 | − |
| MCI/VCI | 8 | 0 | − |