Table 2:
Description of neuropathology by autism-behavior status
| Pathology | Autism Unlikely (GARS AIS <70) |
Autism Possible/ Very Likely (GARS AIS ≥ 70) |
P value |
|---|---|---|---|
| Braak Stage (rating 3–6) N (%) | 32 (82) | 12 (80) | 0.86 |
| Braak Stage 3 | 2 | 0 | − |
| Braak Stage 4 | 2 | 2 | − |
| Braak Stage 5 | 14 | 1 | − |
| Braak Stage 6 | 14 | 9 | − |
| Neocortical/Diffuse LBs | 6 | 2 | 0.59 |
| Limbic predominant & amygdala LBs | 15 | 6 | 0.61 |
| Brainstem predominant LBs | 2 | 0 | 0.50 |
| LATE N (%) | 19 (48) | 7 (44) | 0.80 |
| Vascular Severity Composite (> 0) N (%) |
32 (80) | 9 (56) | 0.070 |
| Global CVD (SD) | 2.37 (2.07) | 1.25 (1.44) | 0.052 |
| CVD: N present/absent | |||
| Frontal | 22/18 | 6/10 | 0.24 |
| Occipital | 14/26 | 3/13 | 0.79 |
| Parietal | 23/17 | 5/11 | 0.076 |
| Temporal | 23/17 | 3/13 | 0.0086 |