Table 1.
Participant characteristics by 10-year ASCVD predicted risk category*
| Variable | All (n=9728) |
0%–5% (n=2383) |
>5%–10% (n=2652) |
>10%–15% (n=1880) |
>15% (n=2813) |
P value |
| Demographics | ||||||
| Age, mean (SD) | 62.61 (5.65) | 58.09 (3.29) | 61.44 (4.76) | 64.01 (5.19) | 66.61 (5.10) | <0.001 |
| Male, no (%) | 5728 (59) | 2203 (92) | 1656 (62) | 870 (46) | 999 (36) | <0.001 |
| Race, no (%) | ||||||
| White | 7528 (77) | 2097 (76) | 2027 (76) | 1400 (75) | 2004 (71) | <0.001 |
| Black | 2200 (23) | 286 (12) | 625 (24) | 480 (26) | 809 (29) | |
| Clinical comorbidities | ||||||
| Hypertension, no (%) | 3875 (40) | 460 (19) | 865 (33) | 780 (42) | 1770 (63) | <0.001 |
| Diabetes, no (%) | 1495 (15) | 47 (2) | 143 (5) | 228 (12) | 1077 (38) | <0.001 |
| Total cholesterol, mean (SD), mg/dL | 201.81 (36.48) | 201.22 (35.14) | 200.63 (36.17) | 201.82 (36.91) | 203.4 (37.56) | 0.034 |
| HDL cholesterol, mean (SD), mg/dL | 50.84 (16.69) | 60.11 (16.59) | 50.88 (15.56) | 48.54 (15.73) | 44.48 (14.83) | <0.001 |
| Current smoker, no (%) | 1431 (15) | 147 (6) | 332 (13) | 330 (18) | 622 (22) | <0.001 |
| Medication use | ||||||
| Statin use, no (%) | 845 (9) | 138 (6) | 232 (9) | 177 (9) | 298 (11) | <0.001 |
| ARIC field centre | ||||||
| Forsyth, NC, no (%) | 2343 (24) | 603 (25) | 642 (24) | 461 (25) | 637 (23) | <0.001 |
| Jackson, MS, no (%) | 1955 (20) | 256 (11) | 570 (22) | 424 (23) | 705 (25) | |
| Minneapolis, MN, no (%) | 2902 (30) | 892 (37) | 777 (29) | 511 (27) | 722 (26) | |
| Washington county, MD, no (%) | 2529 (26) | 632 (27) | 663 (25) | 484 (26) | 749 (27) | |
| Social-risk factors | ||||||
| Educational attainmen | ||||||
| College or above, no (%) | 3843 (40) | 1063 (45) | 1097 (41) | 707 (38) | 976 (35) | <0.001 |
| High school/some college, no (%) | 4110 (42) | 1120 (47) | 1132 (43) | 778 (41) | 1080 (39) | |
| No high school, no (%) | 1764 (18) | 199 (8) | 419 (16) | 395 (21) | 751 (27) | |
| ADI, median (IQR)† | 102 (96.3–108.8) | 100 (93.8–104.9) | 101.9 (96.1–108.9) | 102.5 (96.9–109.6) | 103.2 (97.6–111.5) | <0.001 |
*Risk categories estimated using the pooled cohort equations.
†ADI measures area-level social deprivation and estimated using the census-tract of participants’ five-digit zip code; higher values represent higher area-level social deprivation.
ADI, Area Deprivation Index; ARIC, Atherosclerosis Risk in Communities; ASCVD, atherosclerotic cardiovascular disease; HDL, high-density lipoprotein; MD, Maryland; MN, Minnesota; MS, Mississippi; NC, North Carolina.