Table 4.

Correlation between magnitude of increase in Lp(a) levels and MACE

	Crude model		Adjusted model I		Adjusted model II
	HR (95%CI)	p	HR (95%CI)	p	HR (95%CI)	p
Reference category (n = 181) ≤ 0 mg/dL	1	—	1	—	1	—
1st quartile (n = 90) > 0-2 mg/dL	1.57 (0.90–2.71)	0.111	1.72 (0.98–3.02)	0.058	1.63 (0.94–2.83)	0.084
2nd quartile (n = 64) > 2–4.1 mg/dL	1.59 (0.87–2.92)	0.134	1.65 (0.90–3.02)	0.109	1.56 (0.85–2.86)	0.151
3rd quartile (n = 77) > 4.1–10.1 mg/dL	0.78 (0.38–1.59)	0.488	0.78 (0.38–1.59)	0.485	0.73 (0.35–1.49)	0.381
4th quartile (n = 76) > 10.1 mg/dL	2.29 (1.36–3.84)	0.002	2.00 (1.18–3.42)	0.011	1.78 (0.97–3.28)	0.062

Reference category: patients with an increase in Lp(a)

1st quartile: patients with an increase in Lp(a) level > 0-2 mg/dL

2nd quartile: > 2–4.1 mg/dL. 3rd quartile: > 4.1–10.1 mg/dL.4th quartile: > 10.1 mg/dL

Adjusted model I: adjusted for baseline Lp(a) levels

Adjusted model II:adjusted for on-statin Lp(a) levels