Table 2.

Definition of sICH in the included trials

Trial	Definition of sICH
BASICS	Heidelberg Bleeding Classification - haemorrhagic transformation of infarcted brain tissue, intracerebral haemorrhage both within and outside infarcted brain tissue, intracerebral haemorrhage outside the infarcted brain tissue, or intracranial–extracerebral haemorrhage and an increase of 4 points or more in the NIHSS score or an increase of 2 points or more in 1 of the 11 NIHSS subcategories.
BEST	SITS-MOST criteria - evidence of intracranial haemorrhage on imaging and an increase of 4 or more points on the NIHSS within 24 h after randomisation.
ATTENTION	SITS-MOST criteria - evidence of intracranial haemorrhage on imaging and an increase of 4 or more points on the NIHSS.
BAOCHE	SITS-MOST criteria - evidence of intracranial haemorrhage on imaging and an increase of 4 or more points on the NIHSS.