Fig. 3.

BMSC-exosomes reduce mechanical allodynia by blocking activation of microglia cells. A Immunofluorescence was used for microglia identification; hind paw PWT (B) and PWL (C) of the rats that were intrathecally injected with microglial cells; Immunofluorescence (D) and western blotting (E) were used to detect the expression of OX42 in SDH. Data were shown as mean ± standard deviation. N = 6. *P < 0.05, vs. the sham or PBS group; ^#P < 0.05, vs. the SNL group. BMSC bone marrow mesenchymal stem cell, PWT paw withdrawal threshold, PWL paw withdrawal latency, SDH spinal dorsal horn