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. 2022 Nov 9;22:477. doi: 10.1186/s12903-022-02497-4

Table 1.

Oral manifestations in patients with spa and healthy controls

Characteristics Patients (N = 80) Healthy controls (N = 52) P value
n % n %
Oral manifestation
 Inflammatory lymph node manifestation 5 78.0 1 2.0 0.900
Oral lesions associated with IBD 0.050†
 Present 29 37.0 28 56.0
 Nonpresent 49 63.0 22 44.0
 Indeterminate 2
Type of associated lesion
 Angular Cheilitis 2 2.6 0 0.0 0.200
 Perioral erythema with scaling 1 1.3 0 0.0 0.300
 Aphthous stomatitis 3 3.8 0 0.0 0.091
 Gingivitis 43 55.0 21 42.0 0.001†
 Candidiasis 0 0.0 1 2.0 0.300
 Indeterminate 2
Oral lesions nonassociated with IBD 0.700
 Nonpresent 58 74.0 39 81.0
 Physiological pigmentation 2 2.6 3 6.2
 Traumatic ulcer 7 9.0 2 4.2
 Traumatic fibroma/IFH 2 2.6 1 2.1
 Leukoedema 1 1.3 0 0.0
 Subprosthetic stomatitis 1 1.3 2 4.2
 Nicotinic stomatitis 1 1.3 0 0.0
 Palatine/lingual torus 3 3.8 0 0.0
 Amalgam tattoo 1 1.3 0 0.0
 Mucocele 1 1.3 0 0.0
 Traumatic petechiae 1 1.3 0 0.0
 Leukoplakia 0 0.0 1 2.1
 Indeterminate 2 4

IBD, inflammatory bowel disease; PD, presumptive diagnosis; IFH, inflammatory fibrous hyperplasia

Statistically significant difference (Fisher exact test)