Table 1.
Baseline characteristics
| Parameters | H n = 24 |
P n = 77 |
p value |
|---|---|---|---|
| Age (years) | 47.88 ± 3.04 | 49.55 ± 3.77 | 0.051 |
| Menopausal state n(%) | |||
| Premenopausal | 18 (66.67%) | 47 (61.04%) | 0.798 |
| Postmenopausal | 8 (33.33%) | 30 (38.96%) | |
| BMI (kg/m2) | 22.55 ± 1.26 | 22.43 ± 2.36 | 0.771 |
| WHR | 0.82 ± 0.04 | 0.81 ± 0.05 | 0.243 |
| SBP (mmHg) | 114.42 ± 11.52 | 116.00 ± 16.85 | 0.701 |
| DBP (mmHg) | 74.42 ± 6.15 | 77.42 ± 11.37 | 0.127 |
| Hypertension, n (%) | 0 (0.00%) | 3 (3.90%) | 1.000 |
| Diabetes, n (%) | 0 (0.00%) | 1 (1.30%) | 1.000 |
| FSH (IU/L) | 7.91 (4.80, 24.54) | 68.46 (54.93, 85.64) | <0.05* |
| LH (IU/L) | 5.45 (4.42, 15.84) | 37.33 (28.33, 52.27) | <0.05* |
| E2 (pmol/L) | 216.5 (109.42, 381.90) | 51.65 (32.23, 77.47) | <0.05* |
For normally distributed parameters, the mean was showed ±SD, and p values were calculated using a student’s t-test and for not normally distributed parameters, the median with IQR (P25，P75) was showed, and the p value was calculated using Mann-Whitney U test. Categorical variables are represented by counts, and p value was calculated using Chi-square test
H healthy controls, P Patients with MPS, BMI body mass index, WHR waist hip ratio, SBP systolic blood pressure, DBP diastolic blood pressure, FSH follicle stimulating hormone, LH luteinizing hormone, E2 estradiol
*p < 0.05