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Time course of colonization. (A) Groups of 20 rats were infected with parent strain NG8 ( ) or mutant strain PC3370 (▧) or coinfected with both strains (■), and the number of cells recovered from mandibles of three animals at each time point after infection was enumerated. (B) The percentage of tetracycline-sensitive cells (NG8) recovered from mandibles of coinfected animals was determined as described in Materials and Methods. Error bars indicate standard errors of the means.
