Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Construction of transgenic mice. Transgenic M1-γ34.5 and M2-γ34.5 mice were constructed by inserting the HSV-1 γ34.5 gene into the BglII site of the pGL2-NOS2 expression vector containing the mouse nitric oxide synthase (NOS2) promoter and the XhoI site of the mouse arginase 1 (ARG1) promoter from pGL3-mARG1. Abbreviations: ORF, open reading frame; SV40, simian virus 40; EBV, Epstein-Barr virus; NLS, nuclear localization signal.
