Table 2.
Haplotype frequencies of 17 polymutants (K38A, 1892) of nsp3, T492 of nsp4, (P132, V247, T280, S284) of 3C-like proteinase, I189 of nsp6, P323 of RdRp, I42 of Exonuclease, T9 of envelope protein, (D3, Q19, A63) of membrane glycoprotein, (P13, R203, G204) of nucleocapsid phosphoprotein, all of which locate outside of the spike gene, observed among all Omicron viruses.
| Polymutant haploytype | Frequency | nsp3.L = K38 | nsp3-A1892 | nsp4-T492 | nsp5-P132 | nsp5-V247 | nsp5-T280 | nsp5-S284 | nsp6-I189 | RdRp-P323 | nsp14-142 | E-T9 | M-D3 | M-Q19 | M-A63 | N-P13 | N-R203 | N-G204 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mutant | R | T | I | H | V | T | S | V | L | V | I | G | E | T | L | K | R | |
| RTIHVTSVLVIGETLKR | 4131 | |||||||||||||||||
| RTIHVTSVLVIDETLKR | 52 | D | ||||||||||||||||
| RTIHVTSVLVIGETPKR | 18 | P | ||||||||||||||||
| KAIHCTSILVIDETLKR | 13 | K | A | I | D | |||||||||||||
| RTISVTSVLVVIGEALKR | 11 | A | ||||||||||||||||
| RTIPVTSVLVIDETLKR | 6 | P | D | |||||||||||||||
| RTIHVTSVLVIFQALKR | 5 | D | Q | A | ||||||||||||||
| RTHIYVTSVLVIGETLKT | 5 | Y | ||||||||||||||||
| rare haplotypes (< 5) | 55 |