Fig. 1. Strategy of pattern enrichment analysis for peptide ligand selection. (a) Schematic illustration of the bio-panning and the pattern enrichment analysis. In the analysis, for each of the three-residue position (red circles) patterns, enrichment values of all amino acid patterns were calculated by comparing the sequence dataset of the selected samples with that of the control. (b) Design of randomised peptide library (X, random residue) and the modification reaction with compound 1.
