TABLE 1.
Patient characteristics according to the type of colon resection
| Right hemicolectomy, n (%) | Left hemicolectomy, n (%) | Sigmoid colon resection, n (%) | p a | |
|---|---|---|---|---|
| Overall, N (%) | 673 (100.0) | 167 (100.0) | 284 (100.0) | |
| Basic characteristics | ||||
| Men | 314 (46.7) | 99 (59.3) | 181 (63.7) | <0.001 |
| Age at surgery (y) b | 68.5 (9.7) | 65.8 (9.5) | 66.2 (9.5) | <0.001** |
| Follow-up (mo) c | 57.0 (42–79) | 52.0 (38–79) | 58.0 (41–83) | 0.121 |
| BMI at surgery (kg/m2) b | 26.5 (4.2) | 26.6 (4.3) | 27.6 (4.3) | 0.001** |
| ASA score at surgery | ||||
| I | 106 (16.2) | 34 (21.0) | 63 (23.2) | 0.016* |
| II | 403 (61.6) | 96 (59.3) | 172 (63.2) | |
| III | 140 (21.4) | 32 (19.8) | 34 (12.5) | |
| IV | 5 (0.8) | 0 (0.0) | 3 (1.1) | |
| Charlson Comorbidity Index at surgery c | 2.0 (2–2) | 2.0 (2–2) | 2.0 (2–2) | 0.218 |
| Previous lower abdominal surgery | 239 (35.5) | 56 (33.5) | 80 (28.2) | 0.089 |
| Previous upper abdominal surgery | 45 (6.7) | 9 (5.4) | 20 (7.0) | 0.780 |
| Smoking | ||||
| No | 497 (81.5) | 128 (82.6) | 211 (83.7) | 0.596 |
| Yes | 87 (14.3) | 19 (12.3) | 35 (13.9) | |
| Recently quit | 26 (4.3) | 8 (5.2) | 6 (2.4) | |
| Oncologic characteristics | ||||
| Tumor stage (UICC) | ||||
| I | 145 (21.7) | 37 (22.2) | 102 (36.2) | <0.001** |
| II | 315 (47.2) | 65 (38.9) | 88 (31.2) | |
| III | 188 (28.1) | 61 (36.5) | 85 (30.1) | |
| IV | 20 (3.0) | 4 (2.4) | 7 (2.5) | |
| Distant metastasis | ||||
| No | 645 (96.1) | 155 (92.8) | 264 (93.3) | 0.111 |
| Liver | 16 (2.4) | 6 (3.6) | 11 (3.9) | |
| Lung | 5 (0.7) | 1 (0.6) | 5 (1.8) | |
| Multiple locations | 5 (0.7) | 5 (3.0) | 3 (1.1) | |
| Adjuvant treatment | ||||
| Previous radiotherapy in pelvic region | 14 (2.1) | 4 (2.4) | 8 (2.8) | 0.793 |
| Adjuvant therapy | ||||
| No | 470 (72.6) | 97 (60.2) | 196 (71.3) | 0.013* |
| CAPOX | 78 (12.1) | 38 (23.6) | 44 (16.0) | |
| FOLFOX | 63 (9.7) | 16 (9.9) | 22 (8.4) | |
| Capecitabine | 36 (5.6) | 10 (6.2) | 12 (4.4) | |
| Years since last chemotherapy b | 4.0 (3.0–6.0) | 5.0 (4.0–7.0) | 5.0 (3.0–7.0) | 0.498 |
| Surgical characteristics | ||||
| Setting | ||||
| Elective | 605 (91.1) | 138 (84.1) | 248 (89.5) | 0.032* |
| Emergency | 59 (8.9) | 26 (15.9) | 29 (10.5) | |
| Surgical approach | ||||
| Open | 391 (58.7) | 82 (49.1) | 112 (39.6) | <0.001** |
| Laparoscopic | 219 (32.9) | 70 (41.9) | 145 (51.2) | |
| Conversion | 56 (8.4) | 15 (9.0) | 26 (9.2) | |
| Method of anastomosis | ||||
| Handsewn | 398 (61.9) | 107 (71.3) | 113 (41.1) | <0.001** |
| Stapled | 245 (38.1) | 43 (28.7) | 162 (58.9) | |
| Reconstruction | ||||
| Side-to-end | 26 (4.0) | 17 (10.8) | 127 (51.8) | <0.001** |
| Side-to-side | 600 (92.2) | 87 (55.4) | 59 (24.1) | |
| End-to-end | 25 (3.8) | 53 (33.8) | 59 (24.1) | |
| Temporary stoma | 15 (2.2) | 29 (17.4) | 35 (12.3) | <0.001** |
| Postoperative characteristics | ||||
| Anastomotic leakage | 24 (3.6) | 13 (7.8) | 12 (4.2) | 0.057 |
| Reoperation | 43 (6.4) | 16 (9.6) | 23 (8.1) | 0.305 |
| Other types of complications | ||||
| No | 446 (66.3) | 116 (69.5) | 215 (75.7) | 0.024* |
| 1 complication | 152 (22.6) | 40 (24.0) | 50 (17.6) | |
| >1 complication | 75 (11.1) | 11 (6.6) | 19 (6.7) | |
CAPOX, Capecitabine and Oxaliplatin; FOLFOX, Folinic acid, Fluorouracil, and Oxaliplatin; IQR = interquartile range; UICC, Union for International Cancer Control.
a
P value for comparison of the 3 groups.
b
Values expressed as medan (SD).
c
Values expressed as median (IQR).
* Statistical significance of p < 0.05.
** Statistical significance of p < 0.005.