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. 2022 Nov 9;18(11):e1010931. doi: 10.1371/journal.ppat.1010931

Fig 7. scRNA-seq analysis reveals a CXCL10-driven robust cytotoxic recall response.

Fig 7

(A) UMAP and violin plot showing expression levels of CXCL10 in plasmablasts, cDC_a and CD4_Tcells_2. (B) UMAP and violin plot showing the expression levels of GZMA.1 in CTL and NK cells. (C) PBMC from unvaccinated (n = 8) and BA71ΔCD2-vaccinated (n = 8) pigs were stimulated with BA71ΔCD2 for 48 hours, and the percentages of CD8+, CD4+CD8+, γδ T cells, and CD3-CD8+ cells (NK cells) producing perforin were assessed by flow cytometry. Statistical significance was determined by unpaired two-tailed t-test and is displayed in GraphPad style (p > 0.05 ns, ** p ≤ 0.01, **** p ≤ 0.0001).