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. 2022 Nov 9;17(11):e0275381. doi: 10.1371/journal.pone.0275381

Table 2. Clinical characteristics and CM values in hospitalized patients with COVID-19, depending on baseline HbА1c and DM history.

Parameters Patients w/o DM history Patients with known DM
Group C
(n = 46)
Kruskal Wallis test, Mann-Whitney test,
p-value
HbA1c ≤ 6,0%
Group A
(n = 80)
HbA1c ≥ 6,0%
Group B
(n = 68)
HbA1c at admission, % 5,7 [5,3; 5,8] 6,4[6,2; 6,6] 7,7 [7,2; 8,9] <0,001
p1-2 = 0,003
p1-3<0,001
p2-3 = 0,002
Gender, no. of patients (%) M/F 46/25
65%/35%
34/44
43,5%/56,5%
17/29
37%/63%
0,019
Age, y 50 [41;59] 60,5 [52;74,5] 62 [54;70] <0,001
p1-2 = 0,003
p1-3 = 0,002
p2-3 = 0,126
BMI kg/m2 27,3 [24,6;30,5] 29,8[25;33,9] 30,9 [28,58;36,36] 0,087
Hemoglobin, g/L 143[132,2;149,7] 132[123;143,7] 133,5 [126,5;145,5] 0,113
GFR by EPI,
mL/min/1,73m2
83,2[69,0;102,5] 75,8[56,6;96,7] 74,17[49,7;90,7] 0,231
FPG, mmol/L 5,03[4,9;5,33] 5,33[5,0;5,9] 8,2[7,0;10,6] <0,001
p1-2 = 0,131
p1-3<0,001
p2-3<0,001
ABG, mmol/L 5,78[5,39;6,3] 6,39[5,85;7,02] 10,34[7,47;12,84] <0,001
p1-2 = 0,076
p1-3<0,001
p2-3 <0,001
eAG, mmol/L 6,49[6,21;6,65] 7,61[7,29;7,76] 9,68[8,92;11,63] <0,05
p1-2 = 0,064
p1-3 = 0,004
p2-3 = 0,016

The data is presented as median value (Ме) and interquartile range [25; 75] or mass percentage (%).

HbA1c, glycated hemoglobin; BMI, body mass index; GFR, glomerular filtration rate; FPG, fasting plasma glucose, mmol/L; 24hMPG, 24-hour mean plasma glucose over the last three months; SIH, stress-induced hyperglycemia, mmol/L; ABG, admission blood glucose, mmol/L.