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. 2022 Nov 9;13:6777. doi: 10.1038/s41467-022-34068-0

Fig. 4. Neuro-COVID patients display a vigorous peripheral immune response and specific CSF alterations including analytes with high predictive value for class III development and strong CSF-plasma correlation.

Fig. 4

a Rose plots representing Z-scores of marginalized normalized protein expression (NPX) of 192 soluble proteins in CSF and plasma. For better visualization, analytes have been grouped into ‘inflammatory’ (left panels) and ‘neurological’ (right panels) proteins. b Non-metric multidimensional scaling (NMDS) plots of 192 examined soluble proteins in CSF and plasma. Each patient is presented by one dot, and colored according to healthy controls, CNS inflammatory controls or Neuro-COVID class I-III. The ellipses represent the 95% confidence interval within subgroups. Source data are provided as a Source Data file.