Table.
Clinical Data at Each Time Period.
| At the start of LEN | At the interruption of LEN | At the renal biopsy | Normal range | ||
|---|---|---|---|---|---|
| White blood cells | 6,100 | 7,000 | 5,600 | 3,200-7,900 | /μL |
| Hemoglobin | 8.7 | 9.6 | 7.3 | 11.3-15.0 | g/dL |
| Hematocrit | 27.9 | 30.7 | 22.7 | 34.0-46.3 | % |
| Platelete | 212 | 10.2 | 16.8 | 155-350 | *103/μL |
| Total protein | 8.2 | 6.9 | 6.3 | 6.9-8.4 | g/dL |
| Albumin | 3.5 | 2.9 | 3.4 | 3.9-5.2 | g/dL |
| AST | 19 | 32 | 15 | 13-33 | IU/L |
| ALT | 10 | 19 | 7 | 7-30 | IU/L |
| LDH | 220 | 511 | 209 | 119-229 | IU/L |
| ALP | 402 | 489 | 339 | 117-350 | IU/L |
| γGTP | 15 | 15 | 13 | 9-109 | IU/L |
| Urea nitrogen | 41 | 25 | 16 | 8-21 | mg/dL |
| Creatinine | 1.3 | 1.7 | 1.11 | 0.46-0.78 | mg/dL |
| eGFR | 31.8 | 22.9 | 36.8 | >90 | mL/min/1.73 |
| Uric acid | 8.3 | 7.1 | 7.4 | 2.5-7.0 | mg/dL |
| Na | 138 | 142 | 145 | 139-146 | mmol/L |
| K | 4.4 | 4.5 | 3.8 | 3.7-4.8 | mmol/L |
| Cl | 108 | 111 | 110 | 101-109 | mmol/L |
| Corrected Ca | 9.3 | 9.4 | 9.2 | 8.7-10.1 | mg/dL |
| P | 4.3 | 3.4 | 3.2 | 2.8-4.6 | mg/dL |
| Total bilirubin | 0.7 | 0.9 | 0.6 | 0.3-1.1 | mg/dL |
| CRP | 1.38 | 1.27 | 2.89 | 0.0-0.3 | mg/dL |
| PT | 87.3 | 106 | 90.8 | >75 | % |
| AFP | 2,454.1 | 929.5 | <10.0 | ng/mL | |
| PIVKA-II | 22 | 775 | <40 | mAU/mL | |
| Urine | |||||
| pH | 5.5 | 6.5 | 7.0 | ||
| Specific gravity | 1.024 | 1.007 | |||
| Red blood cell | <1 | <1 | 1-4 | /HPF | |
| Proteinuria | 0.36 | 15.84 | 6.04 | <0.1 | g/day |
| β2-MG | 0.7 | 13.1 | 13.1 | 0.1-1.9 | mg/gCre |
| NAG | 27.3 | 0.8-5.0 | IU/gCre | ||
| α1-MG | 47.73 | mg/gCre |