Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Jun 13;40(11):1624–1633. doi: 10.1038/s41587-022-01342-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Extended Data Fig. 10 — a, Distribution of TmS values for 116 tumor regions from 52 patients of the TRACERx study. Blue triangles denote the maximum TmS for a patient. Blue ‘-‘ denote the median TmS for a patient. b, Pairwise scatter plots and histograms of number of regions, range of TmS, % subclonal CNA, maximum of TmS across regions (TmS_max), and median of TmS across regions (TmS_med) per patient. The number of evaluated patients with at least 2 regions is 30. Spearman correlation coefficient r’s are shown, and the gray lines represent a loess fit. c, KM survival curves of DFS for the 30 patients stratified by % subclonal CNA: high versus low. d-e, KM survival curves of DFS for all 52 patients stratified into two groups by TmS_max (d) and (e) TmS_med, respectively. P values obtained by log-rank tests between high vs. low TmS groups are indicated by asterisks (* P < 0.05, ** < 0.01, *** < 0.001).

Source data