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. 2022 Sep 14;52(6):324–337. doi: 10.1007/s10519-022-10114-x

Fig. 3.

Fig. 3

MR-DoC models with child-rated Moods and Feelings Questionnaire (cMFQ) as exposure, and non-suicidal and suicidal self-harm (NSSH and SSH respectively) as outcomes. MDD = major depressive disorder, PRS = polygenic risk score. Both shared and non-shared correlations (rC and rE) are constrained to zero. Red ovals indicate significance of the causal paths (g1)