Table 2.

Non-metabolite stimulators of bactericidal activity of aminoglycosides

Effector	Hypothesised mechanism	Bacterial species	References
n-butanol	PMF dependent	S. aureus, S. pyogenes, E. faecalis, S. epidermidis,	Lv et al. (2022)
Iron	PMF dependent and PMF independent	E. coli	Kohanski et al. (2007); Ezraty et al. (2013); Dwyer et al. (2015); Ezraty and Barras (2016)
Silver	PMF independent	E. coli, C. difficile	Morones-Ramirez et al. (2013); Herisse et al. (2017)
Rhamnolipids	PMF independent	S. aureus	Radlinski et al. (2019)
Rapid freezing	PMF independent	E. coli, P. aeruginosa	Zhao et al. (2020)

The hypothesised mechanism of aminoglycoside potentiation is displayed along with the bacterial species tested