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. 2022 Nov 9;12:19099. doi: 10.1038/s41598-022-20658-x

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Network analysis. Network plots illustrating protein–protein interactions in (a) EOPE versus healthy pregnancy and (b) LOPE versus healthy pregnancy. Each node represents one protein; and each edge represents a pairwise Pearson correlation between proteins. The networks only show Pearson correlation coefficient > 0.7 or < − 0.7. Node: colour coded according to the functional classification of proteins annotated by DAVID database; size proportional to the corresponding eigenvector centrality (network influence). Edge: colour and length proportional to the Pearson correlation coefficient; width proportional to the scores derived from STRING database.

Source data are provided as a Source Data file.