Table 1.
Summary of patient characteristic (discovery/untargeted proteomics set).
| Characteristics | EOPE (n = 17) | LOPE (n = 11) | Healthy pregnancy (n = 18) |
|---|---|---|---|
| Age (y) | 34.0 ± 7.1 | 33.0 ± 4.0 | 31.1 ± 3.8 |
| BMI (kg/m2) | 27.6 ± 4.8 | 28.3 ± 3.4 | 24.5 ± 5.5 |
| GA at delivery (wk) | 31.3 ± 2.5 ¶& | 37.0 ± 1.9 §& | 39.4 ± 0.9 ¶§ |
| Number of pregnancies (no.) | 1.6 ± 0.9 | 2 ± 0.9 | 1.7 ± 0.8 |
| Systolic blood pressure (mm Hg) | 156.4 ± 26.5 ¶ | 144.4 ± 16.8 § | 113.9 ± 8.5 ¶§ |
| Diastolic blood pressure (mm Hg) | 103.1 ± 10.7 ¶ | 96.9 ± 11.6 § | 72.2 ± 8.1 ¶§ |
| Heart rate (bpm) | 94.6 ± 29.8 ¶ | 82.8 ± 16.5 | 74.4 ± 6.3 ¶ |
| Medications | |||
| Methyldopa (no. [%]) | 17 [100%] | 11 [100%] | 0 [0%] |
| Amlodipine (no. [%]) | 5 [29.4%] | 2 [18.2%] | 0 [0%] |
| Dexamethasone (no. [%]) | 11 [64.7%] | 1 [9.1%] | 0 [0%] |
| Nadroparin calcium (no. [%]) | 3 [17.6%] | 1 [9.1%] | 0 [0%] |
| Diazepam (no. [%]) | 3 [17.6%] | 8 [72.7%] | 0 [0%] |
| Magnesium sulphate (no. [%]) | 4 [23.5%] | 1 [9.1%] | 0 [0%] |
| Nifedipine (no. [%]) | 0 [0%] | 1 [9.1%] | 0 [0%] |
| Low-sodium diet (no. [%]) | 11 [64.7%] | 8 [72.7%] | 0 [0%] |
BMI, body mass index; bpm, beats per minute; EOPE, early-onset pre-eclampsia; GA, gestational age; LOPE, late-onset pre-eclampsia.
¶, P < 0.05 of a characteristic between EOPE and healthy pregnancy groups.
§, P < 0.05 of a characteristic between LOPE and healthy pregnancy groups.
&, P < 0.05 of a characteristic between EOPE and LOPE.