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. 2022 Nov 9;12:19037. doi: 10.1038/s41598-022-23006-1

Table 3.

In vitro hDHODH inhibitory activity of the tested agents.

The tested agent IC50
Allium sativum extract 201.5 (ug/ml) ± 0.044
silymarin standard 133.2 (ug/ml) ± 0.031
Silibinin 121.2 (nM) ± 0.014
Silychristin B 166.1 (nM) ± 0.022
Brequinar 9.717 (nM) ± 0.063

*Data are demonstrated as mean of two tests ± SD.