Table 2.
Alhydrogel® | 100 µg/mL PfRipr5+ Alhydrogel® | 400 µg/mL PfRipr5+ Alhydrogel® | CAF®01 | 100 µg/mL PfRipr5+CAF®01 | 400 µg/mL PfRipr5+CAF®01 | |
---|---|---|---|---|---|---|
Appearance* | Opaque suspension | Opaque suspension | Opaque suspension | Opaque suspension | Opaque suspension | Opaque suspension |
pH** | 7.2 | 6.5 | 7.3 | 7.0 | 6.5 | 7.2 |
Non-adsorbed PfRipr5*** | – | Below detection level of 25 µg/ml | Below detection level of 25 µg/ml | – | Below detection level of 25 µg/ml | Below detection level of 25 µg/ml |
*Appearance was determined by visual inspection.
**pH of the final vaccine formulation was measured, as this may be an indicator of chemical stability.
***Non-adsorbed PfRipr5 protein concentration in the supernatant after the centrifugation was determined by BCA.