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. 2022 Oct 27;13:1002430. doi: 10.3389/fimmu.2022.1002430

Table 2.

Formulation of PfRipr5 with Alhydrogel® and CAF®01.

Alhydrogel® 100 µg/mL PfRipr5+ Alhydrogel® 400 µg/mL PfRipr5+ Alhydrogel® CAF®01 100 µg/mL PfRipr5+CAF®01 400 µg/mL PfRipr5+CAF®01
Appearance* Opaque suspension Opaque suspension Opaque suspension Opaque suspension Opaque suspension Opaque suspension
pH** 7.2 6.5 7.3 7.0 6.5 7.2
Non-adsorbed PfRipr5*** Below detection level of 25 µg/ml Below detection level of 25 µg/ml Below detection level of 25 µg/ml Below detection level of 25 µg/ml

*Appearance was determined by visual inspection.

**pH of the final vaccine formulation was measured, as this may be an indicator of chemical stability.

***Non-adsorbed PfRipr5 protein concentration in the supernatant after the centrifugation was determined by BCA.