TABLE 1.

Associations of early-life upper and/or lower respiratory tract infections with school-age asthma

	Asthma odds ratio (95% CI)
Age 6 months
URTI solely	1.29 (1.19–1.40)**
LRTI solely	2.38 (2.14–2.65)**
Both	2.60 (2.13–3.04)**
Age 1 year
URTI solely	1.18 (1.09–1.27)**
LRTI solely	1.93 (1.77–2.09)**
Both	2.74 (2.49–3.02)**
Age 2 years
URTI solely	1.42 (1.33–1.53)**
LRTI solely	3.06 (2.75–3.40)**
Both	4.40 (4.03–4.80)**
Age 3 years
URTI solely	1.33 (1.24–1.42)**
LRTI solely	4.28 (3.84–4.77)**
Both	4.51 (4.11–4.94)**
Age 4 years
URTI solely	1.33 (1.16–1.52)**
LRTI solely	3.36 (2.80–4.01)**
Both	5.38 (4.41–6.58)**
Age 5 years
URTI solely	1.20 (1.08–1.34)**
LRTI solely	9.06 (7.65–10.72)**
Both	6.63 (5.54–7.94)**

Values are odds ratios with 95% confidence intervals, derived from multilevel logistic regression models. **: p<0.01. Models are adjusted for maternal history of asthma and atopy, ethnicity, education level, smoking during pregnancy, parity and pet keeping, and child's sex, gestational age at birth, birth weight, season of birth, breastfeeding and daycare attendance. URTI: upper respiratory tract infection; LRTI: lower respiratory tract infection.