Table 2.
microRNAs as biomarkers in TB.
| Content of comparison | Sample | Upregulated micro-RNAs | Downregulated microRNAs | Reference |
|---|---|---|---|---|
| Treated versus untreated | Plasma | miR-29a-3p、;miR-155-5p miR-361-5p |
(218) | |
| miR-99b、;miR-29a miR-146a、;miR-26 |
(219) | |||
| Serum | miR-326 | (220) | ||
| miR-346 | (199) | |||
| miR-125a-5p | miR-21-5p、;miR-92a-3p miR-148b-3p |
(221) | ||
| PBMCs | miR-424 | (222) | ||
| Blood | miR-199b-3p、;miR-199a-3p miR-16-5p |
(223) | ||
| Drug-resistant versus pan-susceptible TB patients |
Plasma | miR-320a | (202) | |
| Serum | miR-4433b-5p、;miR-424-5p | (224) | ||
| Exosomes | let7e-5p | miR-197-3p、;miR-223-3p | (225) | |
| Virulent versus avirulent | Macrophages | miR-145 | (226) | |
| MDMs | miR-125b | (70) | ||
| THP-1 cells | miR-4668-5p、;miR-30e miR-1275、;miR-30a miR-3178 |
miR-4484 | (227) |