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Changes in the mRNA expression levels of p53, p21cip1, and Fas in the control and 5-FU groups. In the 5-FU group, the expression level of p53 mRNA increased at 24 h after treatment and 4 d after treatment. The expression level of p21cip1 and Fas mRNA increased at 24 h after treatment. *p<0.05 and **p<0.01.
