FIGURE 2.

Experimental protocol and basic physiological measurements for PCK rats treated with 5‐BDBD. (a) Experimental protocol showing that the 2 groups of PCK male rats were fed on a Nutella diet with 0.5% DMSO (control, N = 7) or 18 mg/kg/day 5‐BDBD (N = 8) for 56 days starting at 4 weeks of age. Total body weight (TBW, b) was measured every day. Heart weight (c), heart weight to total body weight ratio (Heart weight/TBW, d), left kidney weight (LK, e), right kidney weight (RK, f), and 2 kidney weight to total body weight ratio (2 K/TBW, %, g) were measured at the end of the protocol. Data were compared by the Student's t‐test.