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. 2021 Dec 23;149(1):e2021051405. doi: 10.1542/peds.2021-051405

TABLE 2.

Univariable and Full Multivariable Models for Radiographic CAP

Variable Univariable Models, OR (95% CI) Full Multivariable Model, aOR (95% CI)
Demographic
 Age,a y
  1 Reference Referenceb
  2 1.19 (0.81–1.75) 1.39 (1.24–1.55)b
  5 3.54 (2.19–5.74)b 3.55 (2.35–5.36)b
  10 9.43 (6.15–14.48)b 9.06 (4.96–16.56)b
 Sex, male 0.87 (0.66–1.15) 1.02 (0.72–1.45)
Historical
 Fever 3.25 (1.80–5.85)b 0.99 (0.46–2.12)
 Days of Fevera
  1 Reference Referenceb
  2 1.20 (0.79–1.82) 1.47 (1.27–1.70)b
  5 4.73 (2.93–7.65)b 3.44 (2.19–5.41)b
  10 6.51 (4.01–10.59)b 3.93 (2.29–6.75)b
 Cough 2.21 (0.86–5.69) 2.78 (1.00–7.75)
 Difficulty breathing 0.68 (0.49–0.96)b 0.92 (0.56–1.51)
 Immunization 1.38 (0.75–2.56) 1.00 (0.47–2.12)
 Days of illnessa
  1 Reference Reference
  2 1.23 (0.76–1.99) 1.05 (0.98–1.13)
  5 2.68 (1.48–4.86)b 1.23 (0.94–1.61)
  10 5.20 (2.79–9.69)b 1.43 (0.87–2.35)
 Vomiting 1.03 (0.78–1.36) 0.93 (0.66–1.32)
 Wheezing 0.55 (0.41–0.72) 1.01 (0.68–1.50)
 Rapid breathing 0.72 (0.53–0.98)b 0.99 (0.62–1.57)
 Rhinorrhea 0.37 (0.27–0.52)b 0.54 (0.35–0.84)b
 Chest pain 1.63 (1.22–2.19)b 0.90 (0.61–1.35)
 Abdominal pain 1.74 (1.31–2.33)b 0.97 (0.66–1.44)
 Decreased oral intake 1.19 (0.89–1.59) 1.26 (0.87–1.84)
 Decreased urine output 0.95 (0.60–1.51) 0.78 (0.45–1.36)
 Smoke exposure 0.73 (0.55–0.98)b 0.91 (0.64–1.29)
 Pneumonia history 1.39 (0.95–2.05) 1.06 (0.66–1.70)
 Past pneumonia hospitalization 0.73 (0.42–1.26) 0.60 (0.31–1.14)
 Asthma 0.74 (0.55–1.01) 0.80 (0.53–1.21)
Physical examination
 Temperature (degrees Celsius)a
  37 Reference Reference
  38 0.86 (0.58–1.26) 1.13 (0.82–1.56)
  39 0.88 (0.60–1.29) 1.17 (0.76–1.81)
  40 0.82 (0.48–1.41) 1.13 (0.58–2.20)
 Respiratory rate z (95th percentile versus 50th percentile) 1.17 (0.74–1.84) 2.07 (1.27–3.38)b
 Heart rate z (95th percentile versus 50th percentile) 1.09 (0.61–1.96) 1.28 (0.62–2.68)
 Systolic blood pressure z (5th percentile versus 50th percentile) 1.65 (0.90–3.02) 1.59 (0.86–2.94)
 Oxygen saturation
  <92% 0.88 (0.55–1.39) 1.16 (0.85–1.58)
  <94% 0.92 (0.64–1.31) 1.02 (0.84–1.25)
  <96% Reference Reference
  <98% 0.88 (0.56–1.38) 1.05 (0.77–1.44)
  <99% 0.84 (0.53–1.33) 1.00 (0.68–1.46)
 Retractions 0.46 (0.34–0.62)b 0.73 (0.45–1.19)
 Grunting 0.87 (0.49–1.55) 1.71 (0.85–3.44)
 Nasal flaring 0.87 (0.55–1.36) 1.78 (0.96–3.29)
 Head nodding 0.34 (0.10–1.10) 0.92 (0.25–3.37)
 Abdominal pain 1.96 (1.27–3.02)b 1.06 (0.58–1.91)
 Crackles or rales
  None Reference Reference
  Focal 2.20 (1.60–3.02)b 1.39 (0.93–2.09)
  Diffuse 0.65 (0.36–1.18) 0.81 (0.39–1.68)
 Rhonchi
  None Reference Reference
  Focal 1.21 (0.73–1.99) 0.96 (0.52–1.77)
  Diffuse 0.36 (0.24–0.53)b 0.94 (0.57–1.53)
 Wheezing
  None Reference Reference
  Focal 0.97 (0.46–2.03) 1.08 (0.47–2.45)
  Diffuse 0.25 (0.16–0.40)b 0.44 (0.25–0.78)b
 Decreased breath sounds
  None Reference Reference
  Focal 3.51 (2.56–4.81)b 2.20 (1.48–3.27)b
  Diffuse 1.05 (0.59–1.88) 1.23 (0.64–2.36)

aOR, adjusted odds ratio; OR, odds ratio.

a

Restricted cubic splines were applied to quantitative predictors to permit modeling of potentially nonlinear association; predictor values for which odds ratios are displayed were arbitrarily selected to illustrate associations.

b

Variables in which P < .05.