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. 2022 Oct 12;298(11):102588. doi: 10.1016/j.jbc.2022.102588

Figure 1.

Figure 1

CD44v10 is preferentially overexpressed in TNBC tissues. A, CD44v10 expression in BrCa tissues and adjacent normal tissues is shown by immunohistochemistry (IHC). Representative IHC images (left) and analysis of expressions (right) for CD44v10 in 25 pairs of BrCa and matched peritumoral tissues. Statistically significant differences were determined using t-tests. B, representative IHC images (left) and analysis of expression (right) for CD44v10 in a tissue microarray, including luminal BrCas (n = 30), BrCa patients with HER2 overexpression (n = 13), and TNBCs (n = 28). The mean of integrated optical density (IOD) was calculated by the IOD divided by the valid area. Bars represent the mean ± SD values. The ns indicates no significance, ∗p <0.05, ∗∗∗p <0.001. TNBCs, triple-negative breast cancers.