TABLE 2.
10- and 15-Year Growth and Neurodevelopmental Outcomes
| All Mean (SD)or n (%) | No NEC/SIP, Mean (SD)or n (%) | Medical NEC, Mean (SD)or n (%) | Surgical NEC, Mean (SD)or n (%) | SIP, Mean (SD)or n (%) | |
|---|---|---|---|---|---|
| 10-y growth outcomes (N = 889) | |||||
| BMI mean (SD) | 17.8 (4.1) | 17.7 (4.0) | 18.2 (4.3) | 17.0 (3.1) | 17.3 (6.1) |
| z-score | −0.07 (1.46) | −0.06 (1.43) | 0.055 (1.58) | −0.25 (1.36) | −0.51 (1.59) |
| Weight mean (SD) | 33.5 (10.4) | 33.6 (10.2) | 34.4 (11.0) | 31.2 (7.3) | 31.2 (13.4) |
| z-score | −0.19 (1.40) | −0.18 (1.40) | −0.06 (1.33) | −0.43 (1.26) | -0.8 (1.76) |
| Height mean (SD) | 136.4 (8.8) | 136.6 (8.8) | 136.8 (8.8) | 134.8 (7.0) | 132.7 (8.3) |
| z-score | −0.27 (1.25) | −0.27 (1.24) | −0.24 (1.23) | −0.51 (0.95) | −0.8 (1.18) |
| HC mean (SD) | 52.5 (2.4) | 52.6 (2.3) | 52.5 (2.5) | 51.5 (2.2) | 51.6 (3.2) |
| 10-y ND outcomes (N = 889) | |||||
| ADHD | 152 (17.1%) | 122 (18.0%) | 20 (14.7%) | 7 (21.9%) | 3 (10.7%) |
| GMFCS >1 | 72 (8.1%) | 51 (7.7%) | 12 (9.2%) | 3 (9.7%) | 6 (22.2%) |
| Epilepsy | 66 (7.4%) | 54 (7.8%) | 9 (6.6%) | 3 (9.1%) | 0 (0.0%) |
| DAS-II FSIQ | 88.4 (20.0) | 88.9 (19.7) | 88.4 (20.0) | 84.6 (19.5) | 80.4 (24.6) |
| LPA classifications | |||||
| Normal | — | 242 (35.7%) | 43 (31.4%) | 8 (25.8%) | 7 (25.0%) |
| Low-normal | — | 280 (41.3%) | 58 (42.3%) | 12 (38.7%) | 10 (35.7%) |
| Moderate | — | 108 (15.9%) | 24 (17.5%) | 8 (25.8%) | 5 (17.9%) |
| Severely impaired | — | 48 (7.1%) | 12 (8.8%) | 3 (9.7%) | 6 (21.4%) |
| 15-y growth outcome (N = 694) | |||||
| BMI mean (SD) | 23.1 (6.3) | 23.1 (6.5) | 23.9 (5.6) | 20.8 (4.7) | 23.9 (8.8) |
| z-score | 0.41 (1.26) | 0.40 (1.26) | 0.63 (1.25) | −0.25 (1.36) | 0.35 (1.31) |
| Weight mean (SD) | 62.1 (18.7) | 62.0 (18.9) | 64.1 (18.9) | 53.1 (9.0) | 64.8 (24.6) |
| z-score | 0.23 (1.40) | 0.24 (1.36) | 0.40 (1.55) | −0.60 (1.22) | 0.14 (1.63) |
| Height mean (SD) | 163.5 (9.7) | 163.6 (9.5) | 162.9 (9.9) | 160.9 (11.0) | 164.1 (8.6) |
| z-score | −0.44 (1.15) | −0.41 (1.12) | −0.52 (1.20) | −1.07 (1.30) | −0.53 (1.05) |
| HC mean (SD) | 55.6 (2.9) | 55.5 (2.7) | 55.9 (3.5) | 54.2 (2.6) | 55.1 (4.1) |
| 15-y ND outcomes (N = 694) | |||||
| ADD or ADHD | 42 (6.0%) | 31 (6.1%) | 6 (6.1%) | 3 (11.5%) | 2 (12.5%) |
| Epilepsy | 51 (7.3%) | 40 (7.7%) | 8 (8.2%) | 2 (7.7%) | 1 (5.3%) |
| WASI-II FSIQ | 99.6 (17.9) | 100 (17.8) | 98.6 (18.1) | 92.5 (18.4) | 97.5 (18.2) |
| LPA classifications | |||||
| Severe | — | 74 (14.7%) | 19 (19.4%) | 5 (19.2%) | 6 (33.3%) |
| Low-Normal | — | 269 (53.5%) | 48 (49.0%) | 14 (53.8%) | 6 (33.3%) |
| Normal | — | 160 (31.8%) | 31 (31.6%) | 7 (26.9%) | 6 (33.3%) |
ADD, attention-deficit disorder; FSIQ: full-scale IQ; WASI-II: Wechsler Abbreviated Scale of Intelligence-II. —, not applicable.