TABLE 4.

Adjusted Associations between NEC and 10- and 15-Year Outcomes

	No NEC Nor SIP	Medical NEC		Surgical NEC		SIP
		Effect Estimate (β)/OR (95% CI)	P	Effect Estimate (β)/OR (95% CI)	P	Effect Estimate (β)/OR (95% CI)	P
Age-10 outcome
BMI z-score	Referent	0.13 (−0.16 to 0.42)	.38	−0.17 (−0.64 to 0.31)	.49	−0.32 (−0.91 to 0.26)	.28
Weight z-score	Referent	0.15 (−0.09 to 0.40)	.22	−0.20 (−0.64 to 0.24)	.38	−0.44 (−1.07 to 0.20)	.18
Height z-score	Referent	0.06 (−0.16 to 0.29)	.57	−0.14 (−0.47 to 0.19)	.40	−0.31 (−0.75 to 0.12)	.16
DAS-II FSIQ	Referent	0.21 (−3.32 to 3.73)	.91	−2.04 (−9.13 to 5.05)	.57	−3.57 (−11.8 to 4.65)	.39
LPAa	Referent	1.13 (0.80–1.59)	.49	1.46 (0.75–2.83)	.27	1.43 (0.71–2.88)	.32
Age-15 outcome
BMI z-score	Referent	0.24 (−0.04 to 0.53)	.10	−0.55 (−1.09 to −0.01)	.04*	0.08 (−0.60 to 0.75)	.83
Weight z-score	Referent	0.19 (−0.15 to 0.53)	.28	−0.75 (−1.25 to −0.25)	<.01*	0.09 (−0.76 to 0.93)	.84
Height z-score	Referent	−0.08 (−0.34 to 0.18)	.55	−0.65 (−1.16 to −0.14)	.01*	0.03 (−0.53 to 0.59)	.92
WASI-II FSIQ	Referent	−1.62 (−5.65 to 2.41)	.43	−6.51 (−14.2 to 1.14)	.10	−0.07 (−8.50 to 8.36)	.99
LPAb	Referent	0.89 (0.59–1.36)	.60	0.91 (0.42–1.96)	.81	0.90 (0.36–2.24)	.82

Adjusted for Fenton birth weight z-score, GA and sex. LPA OR represents the odds of a worse outcome (impaired). FSIQ, full-scale IQ; OR, odds ratio; WASI-II, Wechsler Abbreviated Scale of Intelligence-II.

^*P ≤ .05.

^aAge-10 LPA outcome classifications were dichotomized to normal/low-normal and moderately impaired/severely impaired.

^bAge-15 LPA variable was dichotomized to normal/low-normal and severely impaired.