Table 2.
Characteristics of eligible participants by gender and vertebra fracture grades identified by Genant’s semi-quantitative criteria.
| Characteristics | Male | Female | ||||||
|---|---|---|---|---|---|---|---|---|
| Non-fracture(n=1031) | Grade 1(n=200) | Grade 2and3(n=36) | p | Non-fracture(n=1834) | Grade 1(n=237) | Grade 2and3(n=99) | p | |
| Age(y) | 62.47 ± 9.16 | 63.57 ± 9.3 | 67.03 ± 9.04 | 0.006▲ | 60.37 ± 8.82 | 65.98 ± 8.06 | 69.77 ± 6.67 | <0.001△ |
| vBMD (mg/cm3), n (%) | 114.47 ± 34.88 | 99.24 ± 30.71 | 84.99 ± 34.74 | <0.001*▲▲ | 105.31 ± 39.63 | 75.00 ± 32.62 | 50.25 ± 23.82 | <0.001*△ |
| Normal | 453 (43.9) | 53 (26.5) | 6 (16.7) | <0.001 | 601 (32.8) | 21 (8.9) | 1 (1.0) | <0.001 |
| Osteopenia | 420 (40.7) | 94 (47.0) | 17 (47.2) | 713 (38.9) | 75 (31.6) | 7 (7.0) | ||
| Osteoporosis | 158 (15.4) | 53 (26.5) | 13 (36.1) | 520 (28.3) | 141 (59.5) | 91 (92.0) | ||
| BMI (kg/m2) | 24.19 ± 3.31 | 24.03 ± 3.27 | 23.77 ± 2.87 | 0.649 | 24.28 ± 3.49 | 24.59 ± 3.93 | 24.38 ± 3.05 | 0.441 |
| WHR | 0.88 ± 0.07 | 0.88 ± 0.07 | 0.88 ± 0.11 | 0.824 | 0.83 ± 0.07 | 0.85 ± 0.07 | 0.86 ± 0.07 | <0.001▲▲▲ |
y, years; p, p-value; vBMD, QCT volumetric bone mineral density; BMI, body mass index; WHR, waist-to-hip ratio.
Continuous variables were shown as mean ± standard deviance, and were tested by ANOVA; ordinal categorical variables were shown as frequency(n) and percentage (%), and were tested by Kruskal-Wallis H tests.
*, the p -value is always<0.001 before and after being adjusted by age.
▲, male age shows no significant difference between Grade 1 group and other two groups, while age of non-fracture group is significantly different from Grade 2and3 group with p=0.010.
△,the p-value of all comparison among groups <0.001.
▲▲,the p-value among Grade 1 group and Grade 2and3 group =0.065, while p-value of other pairs<0.001.
▲▲▲, the p-value among Grade 1 group and Grade 2and3 group =1.000, while p-value of non-fracture group vs. Grade 1 group<0.001 and p-value of non-fracture group vs. Grade 2and3 group=0.002.